Society for Economic Botany/BSA Economic Botany Section
Rose, Janna .
Bacterial Inhibition and Cytotoxic Properties of Plants used to Treat Diarrhea in Central Anatolian Villages.
In this study, 15 Central Anatolian plant extracts were evaluated for their safety and their efficacy in inhibiting the growth of 21 bacterial strains that commonly infect the human intestinal tract and cause diarrhea. Ethnobotanical research was carried out in Central Anatolia for one year, beginning in September 2008. Following interviews and a thorough literature review, plants used to treat diarrhea were collected for research. Voucher specimens were deposited in Gazi University┬┤s Herbarium. Plant materials were collected and processed in bulk, with methanolic and aqueous extracts prepared from culturally relevant parts of the plants for a total of 34 extracts. An antibacterial assay was carried out using microtiter broth dilutions to CLSI standards, and an Alamar Blue Cytotoxicity Assay was used to evaluate the safety of the plants for human ingestion. The percent inhibition was used to calculate the effectivenessof the 34 extracts in inhibiting one or more of the 21 bacterial strands. Rosa canina, Hypericum perforatum, Vitex agnus-castus, and Rhus coriaria showed significant inhibition at low concentrations (32, 16, 8, and 4ug/ml) against 8 bacteria (Enterococcus faecalis, Klebsiella pneumoniae, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, Shigella flexneri, Vibrio parahaemolyticus, and Yersinia pseudotuberculosis). Further evaluation of these Turkish plants could lead to an easily accessible, readily available plant-based remedy for diarrhea in the region.
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1 - Florida International University, Biological Sciences, 11200 SW 8th Street, Owa Ehan 167, Miami, FL, 33199, USA
Presentation Type: Oral Paper:Papers for Sections
Location: Maryland Room/Chase Park Plaza
Date: Monday, July 11th, 2011
Time: 9:00 AM